# GLP-1 agonists and muscle

3 papers in the library, strongest Moderate.

**Graded Moderate**: Scoping review of human studies on GLP-1 receptor agonists in older adults, though data on muscle mass and physical performance remain limited and inconsistent.

## Papers (3)

- [Why GLP-1 Weight Loss Can Cost You Muscle After 60](https://longevity-cities.com/en/research/why-glp-1-weight-loss-can-cost-you-muscle-after-60) · Moderate · 2026 · Current nutrition reports
- [Why Muscle Quality Matters So Much on GLP-1 Weight Loss Drugs](https://longevity-cities.com/en/research/why-muscle-quality-matters-so-much-on-glp-1-weight-loss-drugs) · Preliminary · 2026 · Journal of Yeungnam medical science
- [A New Drug Combo May Protect Muscle During Ozempic-Style Weight Loss](https://longevity-cities.com/en/research/a-new-drug-combo-may-protect-muscle-during-ozempic-style-weight-loss) · Preliminary · 2026 · Proceedings of the National Academy of Sciences of the United States of America

## How this map is computed

A mark's size is the number of papers we hold on that pairing. It is a count, not a weighting by study design or sample size.

The fill shows the strongest grade in the cell. One Strong paper among four Preliminary ones still fills it dark, so open the cell to see the rest.

Grades and verdicts are assigned by a named person, never by counting.

An empty cell is a finding: nobody in our library has run that trial yet.

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_Canonical: https://longevity-cities.com/en/evidence/glp-1/muscle · Part of Longevity Cities_