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Biological age
DEBiologisches Alter
Biological age is an estimate of how old your body seems to be. It is based on physiological and molecular markers, not on the calendar. You can derive it several ways. Options include blood biomarkers (like PhenoAge), DNA-methylation patterns (epigenetic clocks), grip strength, gait speed, or organ-specific protein signatures. It is widely used in longevity research. But no single biological-age measure is yet endorsed by regulators as a clinical endpoint. And how well each one is validated varies a lot.
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Sources
- Horvath S, Raj K. (2018). DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nature Reviews Geneticsdoi:10.1038/s41576-018-0004-3
- Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, et al. (2018). An epigenetic biomarker of aging for lifespan and healthspan. Aging (Albany NY)doi:10.18632/aging.101414
Related studies from the research library
- Your Epigenetic Age May Predict How Fast Your Grip and Memory FadeEvidence: Moderate
- A Blood Test for Muscle and Bone Age Flags Who Ages FasterEvidence: Moderate
- A Simple Aging Clock Using Routine Blood Tests Predicts Disease RiskEvidence: Strong
Used in
Papers· 13
- Old Blood Cells Turned Into Neural Stem Cells Shed Most of Their Epigenetic AgePreliminary
- Your Epigenetic Age May Predict How Well Your Body Holds Up as You AgeModerate
- New Trial Will Test Whether Taurine Improves Blood Sugar and Slows AgingPreliminary
- Combining Wearables With Blood Proteins Sharpens Biological Age TestsPreliminary
- Exercise Linked to Younger Biological Age, But Effect Is ModestModerate
- Three Ways to Measure Biological Age All Predict Heart DiseaseStrong
- When Your Body Ages Faster Than Your Birthday, Your Heart Pays the PriceStrong
- Tracking Your 'Biological Age' Over Time May Predict Death Risk Better Than a Single SnapshotModerate
- When Your Body Ages Faster Than Your Age, Muscle Loss Starts EarlyModerate
- Faster Biological Aging Linked to Worsening Brain Small Vessel DiseaseModerate
- Centenarians Show a Distinct Metabolic Profile Tied to Bile Acids and NAD+Moderate
- Loneliness and Social Isolation Are Linked to Faster Biological AgingModerate
+1 more paper
Articles· 7
- What your grip strength quietly says about your lifespan
- Is longevity only for the rich?
- Why Medicine Still Reacts Too Late
- From Quantified Self to Quantified Tribe: Welcome to Germany’s Longevity Ecosystem
- Bryan Johnson's Blueprint Raises $60 Million: Inside the Longevity Startup in 2025
- Skin Longevity: What We Learned from Dr. Mana Witt at Longevity Hamburg’s Launch Event
- Longevity School Course by Dr. Oliver Zolman: Reverse Aging with Science