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Nutrition & supplements

Curcumin

Curcumin is the principal polyphenol in turmeric (Curcuma longa) and modulates NF-kB, Nrf2, and other inflammatory and oxidative pathways. Standard curcumin has very low oral bioavailability; supplements typically use piperine, phospholipid, or nanoparticle formulations. Meta-analyses suggest modest reductions in inflammatory markers, joint pain, and lipid measures, but effects vary by formulation and study quality. Evidence for direct longevity benefits in humans is limited.

Last reviewed:

Sources

  1. Hewlings SJ, Kalman DS. (2017). Curcumin: A Review of Its Effects on Human Health. *Foods*doi:10.3390/foods6100092
  2. Aggarwal BB, Sundaram C, Malani N, Ichikawa H. (2007). Curcumin: the Indian solid gold. *Advances in Experimental Medicine and Biology*doi:10.1007/978-0-387-46401-5_1

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