NMN Plus Apigenin May Protect Aging Muscle and Bone Better Together
This study suggests combining NAD boosters with apigenin may better preserve musculoskeletal health in aging.
In aged mice, combining the NAD booster NMN with apigenin (a compound found in parsley and chamomile) reduced cartilage breakdown, bone loss, and muscle wasting. The combo works by both producing more NAD+ and blocking enzymes that consume it. Treated mice also showed better exercise capacity. The benefits appeared to work through SIRT3 activation and changes in gut bacteria that produce a helpful fat molecule.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Topics
Related Studies
All researchNAD+ Decline in Menopause: Real Biology, Thin Human Evidence So Far
NAD+ is the molecule your cells use to make energy and repair DNA, and levels drop as you age.
A Common Flame Retardant Made Alcohol Damage Worse, and NAD+ Reversed It
Zebrafish exposed to DBDPE, a flame retardant found in furniture and electronics, handled an alcohol hit much worse than usual.
Why Low NAD+ May Push Insulin-Making Cells Into Self-Inflicted Inflammation
In cells and animals, oxidative stress drained NAD+ inside the insulin-producing cells of the pancreas, flipping a chemical switch that set…
