Skip to content
Journal ArticleObservational StudyJAMA network open·Graded and published ·Last edited

Your Brain May Slow Down Years Before a Heart Attack or Stroke

Graded Moderatenested case-control study in 9,435 adults aged 65+ over 11 years, though observational data show association only and the pattern did not hold for nonfatal heart attacks.

Design
Observational Study
Participants
9,435
Duration
Funding
Key Insight

This study suggests unexplained cognitive changes in older adults may warrant a closer look at heart health.


In older adults, thinking skills started declining 3 to 8 years before they had a major cardiovascular event like a stroke or heart failure. The drops showed up in memory, processing speed, and verbal fluency compared to people who stayed healthy. This hints that heart disease and brain aging share deep roots, and subtle cognitive changes might be an early warning sign.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.