Forschungs-Digest
Forschungsbibliothek
Peer-reviewed Papers aus Top-Journals, zusammengefasst und nach Evidenzstärke bewertet. Updates jeden Mo, Mi & Fr.
22.–28. Mär 2026
2 StudienWhy Your Skin Never Forgets Inflammation, Even Years Later
In mice, skin stem cells can hold lifelong "memories" of past inflammation like psoriasis flares. These memories are stored as epigenetic changes. Specific DNA sequences rich in CpG patterns keep the memory accessible through cell divisions. This means once skin has been inflamed, its stem cells stay primed to react faster and stronger to future triggers.
Lab-on-a-Chip Mimics Decades of Human Aging in Just 4 Days
Researchers built a tiny organ-on-a-chip using human stem cells to model how fat tissue and the liver age together. By exposing it to blood serum from older people, the chip reproduced decades' worth of aging hallmarks in just 4 days. These included DNA damage and gene expression shifts seen in actual aged tissues. The system also revealed sex-based differences in aging and how fat aging spills over to affect the liver.
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